Current breast cancer clinical trials

Home: Educational Supplement: Section 8

SELECT PUBLICATIONS

Baselga J. Clinical trials of Herceptin(trastuzumab). Eur J Cancer 2001;37 Suppl 1:S18-24. Abstract

Baselga J et al. Phase II study of weekly intravenous trastuzumab (Herceptin) in patients with HER2/neu-overexpressing metastatic breast cancer. Semin Oncol 1999;26:78-83. Abstract

Berry DA et al. HER-2/neu and p53 expression versus tamoxifen resistance in estrogen receptor-positive, node-positive breast cancer. J Clin Oncol 2000;18:3471-3479. Abstract

Burris HA 3rd. Docetaxel (Taxotere) plus trastuzumab (Herceptin) in breast cancer. Semin Oncol 2001;28:38-44. Abstract

Burstein HJ et al. Clinical activity of trastuzumab and vinorelbine in women with HER2-overexpressing metastatic breast cancer. J Clin Oncol 2001;19:2722-30. Abstract

Burstein HJ et al. Preoperative Herceptin and paxlitaxel (Taxol) for HER2 overexpressing (HER2+) stage II/III breast cancer. Proc ASCO 2001;Abstract 100.

Carey LA et al. Safety and efficacy of 4AC followed by paclitaxel plus trastuzumab in high risk breast cancer patients. Proc ASCO 2001;Abstract 1856.

Cobleigh MA et al. Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease. J Clin Oncol 1999;17:2639- 2648. Abstract

Couturier J et al. Strong correlation between results of Fluorescent in situ hybridization and immunohistochemistry for the assessment of the ERBB2 (HER-2/neu) gene status in breast carcinoma. Mod Pathol 2000;13(11):1238-1243. Abstract

Horton J. HER2 and trastuzumab in breast cancer. Cancer Control 2001;8(1):103-110. Full-Text

Jacobs TW et al. Comparison of fluorescence in situ hybridization and immunohistochemistry for the evaluation of HER-2/neu in breast cancer. J Clin Oncol 1999;17:1974-1982. Abstract

Knoop AS et al. Value of epidermal growth factor receptor, HER2, p53, and steroid receptors in predicting the efficacy of tamoxifen in high-risk postmenopausal breast cancer patients. J Clin Oncol 2001;19:3376-3384. Abstract

Lebeau A et al. HER-2/neu analysis in archival tissue samples of human breast cancer: Comparison of immunohistochemistry and fluorescence in situ hybridization. J Clin Oncol 2001;19:354-363. Abstract

Mass R. The role of HER-2 expression in predicting response to therapy in breast cancer. Semin Oncol 2000;27(6 Suppl 11):46-52; discussion 92-100. Abstract

Mass RD et al. Improved survival benefit from Herceptin (trastuzumab) in patients selected by fluorescence in situ hybridization (FISH). Proc ASCO 2001;Abstract 85.

Masood S, Bui MM. Assessment of Her-2/neu overexpression in primary breast cancers and their metastatic lesions: An immunohistochemical study. Ann Clin Lab Sci 2000;30:259-65. Abstract

Nabholtz JM, Slamon D. New adjuvant strategies for breast cancer: Meeting the challenge of integrating chemotherapy and trastuzumab (Herceptin). Semin Oncol 2001;28:1-12. Abstract

Onody P et al. Fluorescence in situ hybridization and immunohisto-chemical assays for HER-2/neu status determination. Application to node-negative breast cancer. Arch Pathol Lab Med 2001;125:746-750. Abstract

Osoba D, Burchmore M. Health-related quality of life in women with metastatic breast cancer treated with trastuzumab (Herceptin). Semin Oncol 1999;26:84-8. Abstract

Paik S, Park C. HER-2 and choice of adjuvant chemotherapy in breast cancer. Semin Oncol 2001;28(4):332-5. Abstract

Pegram MD, et al. Trastuzumab and chemotherapeutics: Drug interactions and synergies. Semin Oncol 2000;27:21-5; discussion 92- 100. Abstract

Pegram MD. Docetaxel and herceptin: Foundation for future strategies. Oncologist 2001;6 Suppl 3:22-5. Abstract

Pegram MD et al. Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment. J Clin Oncol 1998;16:2659-71. Abstract

Perez EA, Hortobagyi GN. Ongoing and planned adjuvant trials with trastuzumab. Semin Oncol 2000;27:26-32; discussion 92-100. Abstract

Persons DL et al. Fluorescence in situ hybridization (FISH) for detection of HER-2/neu amplification in breast cancer: A multicenter portability study. Ann Clin Lab Sci 2000;30:41-8. Abstract

Ravdin PM. Should HER2 status be routinely measured for all breast cancer patients? Semin Oncol 1999;26(4 Suppl 12):117-23. Abstract

Seidman AD et al. Weekly trastuzumab and paclitaxel therapy for metastatic breast cancer with analysis of efficacy by HER2 immunophenotype and gene amplification. J Clin Onco 2001;19:2587-95. Abstract

Slamon DJ et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 2001;344:783-92. Abstract

Slamon D, Pegram M. Rationale for trastuzumab (Herceptin) in adjuvant breast cancer trials. Semin Oncol 2001;28:13-9. Abstract

Sparano JA. Cardiac toxicity of trastuzumab (Herceptin): Implications for the design of adjuvant trials. Semin Oncol 2001;28:20-7. Abstract

Smith I. Future directions in the adjuvant treatment of breast cancer: The role of trastuzumab. Ann Oncol 2001;12(Suppl 1):S75-S79. Abstract

Tubbs RR et al. Discrepancies in Clinical Laboratory Testing of Eligibility for Trastuzumab Therapy: Apparent Immunohistochemical False-Positives Do Not Get the Message. J Clin Oncol 2001;19:2714- 2721. Abstract

Vogel CL et al. Superior outcomes with Herceptin (trastuzumab) (H) in fluorescence in situ hybridization (FISH)-selected patients. Proc ASCO 2001;Abstract 86.

Yamauchi H, Stearns V, Hayes DF. When is a tumor marker ready for prime time? A case study of c-erbB-2 as a predictive factor in breast cancer. J Clin Oncol 2001;19:2334-56. Abstract

Top

 

Additional Sections:
1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 |

Section 8:
Herceptin ® (trastuzumab) as adjuvant therapy
Page 1
Select Publications

 

Additional Sections:

1
Breast cancer clinical trials
2
Management of the axilla
3
Radiation therapy for primary breast cancer
4
Optimal use of adjuvant tamoxifen and ovarian ablation
5
Aromatase inhibitors in the adjuvant setting
6
Faslodex: An estrogen receptor downregulator
7
Optimal use of adjuvant chemotherapy
8
Herceptin as adjuvant therapy
9
Neoadjuvant systemic therapy
10
Bisphosphonates as adjuvant therapy
11
Other breast cancer clinical trials
12
Breast cancer training opportunities and clinical trials at Northwestern University
 

Search our site
Home · Contact us
Terms of use and general disclaimer