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Home:
Educational
Supplement: Section 12
Section 12
Breast
cancer training opportunities and clinical trials at Northwestern
University
- Fellowship
Programs
BREAST
SURGERY FELLOWSHIP
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1. GENERAL
The
modern management of breast disease requires an in-depth
knowledge of not only surgery, but breast imaging, image-directed
biopsy techniques, pathology, radiation oncology and medical
oncology. This fellowship is designed to enhance the basic
knowledge of the management of breast disease acquired
by a general surgical trainee, particularly in the nonsurgical
disciplines.
Successful
completion of a 5-year accredited program in general surgery
is a prerequisite.
2.
OBJECTIVES
The breast fellowship will enable the resident to acquire
an advanced body of knowledge and level of skill in the
management of breast disease in order to assume a leadership
role in teaching and research in the field.
This will include:
- an understanding of the classification and evaluation
of mammographic abnormalities;
- knowledge of the indications, techniques and complications
of image-guided breast biopsy;
- understanding of the basic techniques of gross breast
specimen evaluation and processing,
recognition of basic breast pathology and knowledge of
pathologic prognostic factors;
- ability to counsel patients on treatment options for
the local therapy of breast cancer;
- evaluation of breast problems in an office-based setting;
- understanding the indications, complications, techniques,
results and biology of breast irradiation;
- understanding the indications, results and basic biology
of systemic therapy for breast cancer; and
- understanding the biology, evaluation and treatment
of benign breast disease.
In addition,
individuals completing this training program will be able
to:
- Evaluate the clinical literature in breast disease critically
and contribute to the field.
- Teach the specialty of breast disease.
- Organize a multidisciplinary approach to breast cancer
care.
3.
CURRICULUM
- Knowledge Base
- Evaluation and management of benign breast disease
- Breast cancer risk assessment
- Breast cancer genetics
- Screening and diagnostic mammography
- Natural history and pathology of benign and malignant
breast disease
- Selection of local therapy, contraindications,
local recurrence, expected outcomes
- Radiation therapy postmastectomy and as part of
breast conservation
- Adjuvant systemic chemotherapy and endocrine therapy
- Preoperative workup and postoperative monitoring
- Psychological and legal aspects of breast cancer
care
- Skills
- Stereotactic or ultrasound-guided core biopsy
- Cosmetic breast-conserving surgery or biopsy
- Skin-sparing mastectomy
- Axillary dissection with intercostobrachial nerve
preservation
- Interpretation of mammograms and ultrasound
- Sentinel node biopsy
4.
ORGANIZATION AND FACULTY
- Program Director - The program will be directed by
Monica Morrow, MD, Director of the Lynn Sage Comprehensive
Breast Program
- The program will be in the Department of Surgery and
the Division of Surgical Oncology
- Faculty
- The primary surgical faculty for the program will
be Dr. Monica Morrow, Dr. Seema Khan and Dr. Valerie
Staradub.
- The participating surgical faculty at Evanston
Hospital will be Dr. David P. Winchester, Dr. Stephen
Sener and Dr. David J. Winchester.
- Supervision of the fellow in nonsurgical disciplines
will be the responsibility of the individual in that
section designated as the leader in the breast cancer
efforts in mammography, pathology, radiation oncology
and medical oncology.
5.
RELATIONSHIP TO GENERAL SURGERY RESIDENCY
The
fellow will not be responsible for the supervision of general
surgery residents.
Six months of the fellowship will be spent on nonsurgical
rotations. The integrity of the general surgery residency
will be maintained during the months of surgical rotation
(four months at Northwestern Memorial Hospital, two months
at Evanston Hospital) by scheduling fellows and general
surgery chief residents to cover different attendings. For
example, four surgical attendings practice in the breast
center. The fellow will spend two months with two attendings
and two months with two other attendings. During each of
these blocks, two other office practices will be available
to the general surgery chief resident. At present, more
than 600 primary breast cancers are treated at each of the
institutions participating in the fellowship. Many of these
cases are done by attending staff due to lack of appropriate
resident coverage, so the participation of the fellow in
selected cases will not make an impact on the operative
experience of the general surgery residents.
6.
APPLICATION AND SELECTION PROCESS
Written
application, including a copy of the candidate's curriculum
vitae and letters of recommendation, will be solicited.
Appropriate
candidates will be interviewed by Dr. Morrow and other participating
surgical faculty.
Applicants
will be selected by faculty committee based on past record
of achievement, recommendations and the interview process
without regard to gender or race.
7.
EVALUATION
Residents
will be evaluated by participating faculty for each of the
rotations in the program. In addition to an overall evaluation,
faculty will assess whether the resident has met the goals
for curriculum and skills acquisition.
The
program director and executive committee will meet with
the resident at three months, six months and 11 months to
provide performance feedback.
Successful
completion of the program will be contingent upon meeting
curricular and skills requirements as judged by evaluations.
In addition, the trainee must (1) complete at least one
scholarly project suitable for publication, (2) make one
local presentation and (3) show evidence of teaching medical
students and residents.
8.
ADMINISTRATIVE STRUCTURE
The
fellowship will be part of the McGaw Medical Center Graduate
Medical Education Program. All policies of the McGaw Medical
Center GME Program will apply to the fellowship, fellows
and faculty.
Fellows
will be recommended for appointment to the faculty of Northwestern
University at the level of Clinical Instructor in Surgery.
Any faculty appointment will be co-terminous with the duration
of the fellowship.
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ROTATION
LENGTH
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FELLOWSHIP
LOCATION
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FELLOWSHIP
ACTIVITIES
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4
months
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Northwestern
Memorial Hospital
Lynn Sage Breast Center |
WHILE
AT NORTHWESTERN MEMORIAL HOSPITAL
- Weekly
Breast Conference, Monday 5:00 p.m.
Prepare, present cases
- Weekly
Breast Cancer Journal Club
Dr. Jordans Laboratory
- Weekly
Surgical Oncology Conference
Wednesday 5:00 p.m. when breast topic presented
WHILE
AT EVANSTON HOSPITAL
- Weekly
Breast Conference
Prepare present cases
1 teaching session for third-year students
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2
months
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Evanston
Hospital
Breast Cancer |
2
months
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Northwestern
Memorial Hospital
Mammography |
2
months
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Northwestern
Memorial Hospital
Medical Oncology Outpatient Clinics |
1
months
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Northwestern
Memorial Hospital
Pathology
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1
months
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Northwestern
Memorial Hospital
Radiation Oncology/Genetic Counseling |
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BREAST
IMAGING FELLOWSHIP
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We are
offering one-year fellowship positions for July 1, 2002 -2003
at the Lynn Sage Comprehensive Breast Center of Northwestern
Memorial Hospital. The Center provides all-inclusive care
for the patient with breast disease. Our fellowship program
provides extensive training in film-screen and full-field
digital mammography, breast ultrasound and interventional
techniques including stereotactic and ultrasound-guided needle
biopsies, sentinel lymph node mapping and ductography. Nearly
40,000 breast imaging exams and procedures were performed
in 2000 with continued annual growth.
The program
also includes rotations in breast surgery, pathology and radiation
oncology to ensure that the fellows gain experience in these
closely related specialties. Attendance at the weekly multidisciplinary
breast conference provides a comprehensive clinical perspective
on breast cancer care. In addition, the fellows will have
an opportunity to participate in ongoing research projects
including full-field digital mammography and breast MRI.
We are
currently accepting applications and will be conducting personal
interviews. Applicants should be board-certified or board-eligible
in diagnostic radiology.
Ellen
Mendelson, MD
Director, Section of Breast Imaging
Northwestern Memorial Hospital
Lynn Sage Comprehensive Breast Center
Galter Pavilion, Rm. 13-136
675 N. St. Clair
Chicago, IL 60611
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TRAINING
PROGRAM IN THE MOLECULAR BIOLOGY OF BREAST NEOPLASIA
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OVERVIEW
The Robert
H Lurie Comprehensive Cancer Center has made significant advances
in establishing a premier Breast Cancer Research Program at
Northwestern University. The Training Program in the Molecular
Biology of Breast Neoplasia enables four predoctoral students
and two postdoctoral fellows per year to receive state-of-the-art
training in breast cancer biology, utilizing the tools of
molecular biology, genetics and biochemistry to study the
complex process of breast neoplasia. Trainees participate
in a weekly Journal Club, a multidisciplinary course in breast
cancer and monthly breast cancer research meetings. The preceptors
of this program are well-established investigators with NIH-funded
research programs.
Program
Director:
V Craig Jordan, PhD, DSc
Diana Princess of Wales Professor of Cancer Research
Robert H Lurie Comprehensive Cancer Center
Administrative
Director:
Robin Leikin, PhD
Research Assistant Professor
Robert H Lurie Comprehensive Cancer Center
The Robert
H Lurie Comprehensive Cancer Center is an NCI-funded cancer
center. The Cancer Center Director is Steven T Rosen, MD,
FACP, Professor of Medicine.
Predoctoral
students must be enrolled in a graduate program (IGP or IBiS)
at Northwestern University. Postdoctoral fellows must have
received their PhD within the last two years.
Applicants
should send their curriculum vitae, statement of research
interests, selection of two potential mentors from Program
Faculty and two letters of reference to:
Robin
Leikin, PhD
Robert H Lurie Comprehensive Cancer Center
Northwestern University
303 E. Chicago Avenue
Chicago, IL 60611
(312) 908-9229
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PROGRAM
FACULTY
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Brian
Hoffman, PhD
Professor
Department of Chemistry
Imaging of breast cancer
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J.
Larry Jameson, MD, PhD
Professor
Department of Medicine
Mutations in endocrine tumors |
V.
Craig Jordan, PhD, DSc
Professor
Cancer Center
Estrogen receptor signal transduction pathway |
Mary
Hunzicker-Dunn, PhD
Professor
Department of Cell and Molecular Biology
Protein kinase C
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Jonathan
Jones, PhD
Professor
Department of Cell and Molecular Biology
Cell adhesion molecules |
Daniel
Linzer, PhD
Professor
Department of Biochemistry, Molecular
Biology & Cell Biology |
Gerald
Soff, MD
Associate Professor
Department of Medicine
Angiogenesis
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Bayar
Thimmapaya, PhD
Professor
Department of Microbiology/Immunology
Nuclear targets of matrix signaling
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Richard
Morimoto, PhD
Professor
Department of Biochemistry, Molecular
Biology & Cell Biology
Heat shock proteins
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Sharon
Stack, PhD
Associate Professor
Department of Obstetrics and Gynecology
Cell matrix proteins
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Debra
Tonetti, PhD
Assistant Professor
Cancer Center
Tamoxifen-resistant breast cancer |
H.
William Schnaper, PhD
Associate Professor
Department of Pediatrics
Endothelial cell signaling
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Paula
Stern, PhD
Professor
Department of Molecular Pharmacology & Biological
Chemistry
Hormones and signal transduction in bone funded by the
U.S. Army Medical Research & Materiel Command |
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POSTDOCTORAL
TRAINING PROGRAM IN CLINICAL ONCOLOGY RESEARCH
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INTRODUCTION
The Robert
H Lurie Comprehensive Cancer Center of Northwestern University
is an NCI-funded cancer center. The Clinical Oncology Research
Training Program at the Cancer Center enables four postdoctoral
fellows per year to receive state-of- the-art training in
one of four areas:
- viral carcinogenesis
- tumor invasion, metastasis and angiogenesis
- hormones and signal transduction in cancer
- cancer genes and molecular regulation
Trainees
have the opportunity to carry out laboratory research as well
as to explore the applied relevance of their research. The
laboratory preceptors of this program are well-established
investigators with NIH-funded research programs. A structured
educational curriculum, clinical rotations and seminar series
complement the laboratory training.
Program
Director:
Steven T Rosen, MD,
Professor and Director
Robert H Lurie Comprehensive Cancer Center
Program
Co-Director:
Leo I Gordon, MD
Professor, Department of Medicine
Chief, Division of Hematology/Oncology
Program
Co-Director:
Sharon Murphy, MD
Professor, Department of Pediatrics
Chief, Division of Hematology/Oncology
Administrative
Director:
Robin Leikin, PhD
Research Assistant Professor
Robert H Lurie Comprehensive Cancer Center
PROGRAM
OVERVIEW
The Clinical
Oncology Research Training Program of the Robert H Lurie Comprehensive
Cancer Center offers two years of laboratory research through
the adult or pediatric divisions of Hematology/Oncology. Second-
or third - year fellows enrolled in accredited programs in
adult or pediatric hematology/oncology interested in laboratory
research can apply to the Cancer Centers NCI-funded
training program, the Clinical Oncology Research Training
Program. Both a basic science faculty member and a clinical
science mentor supervise fellows selected into the program.
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CURRICULUM
- Laboratory research (80% effort)
- Coursework in Tumor Cell Biology and Carcinogenesis
- Weekly Laboratory Journal Club meeting
- Biweekly Oncology Research Journal Club
- Monthly meeting with clinical mentor
- Annual translational research retreat
- Annual research presentation
- Quarterly basic science symposia and minisymposia
- Colloquium on ethics in biomedical research
- Outpatient clinic one day per week
CLINICAL
MENTORS
Al Benson,
MD
Richard Burt, MD
Peter Gann, MD
Leo Gordon, MD
Bill Gradishar, MD
Morris Kletzel, MD
Timothy Kuzel, MD
Hau Kwaan, MD
Sharon Murphy, MD
Martin Tallman, MD
Jamie Von Roenn, MD
Jane Winter, MD
LABORATORY
PRECEPTORS
Fellows
select a laboratory research mentor from the following faculty
listed by their Cancer Center program affiliation.
Cancer
Genes and Molecular Regulation
Susan Cohn, MD
J. Douglas Engel, PhD
Philip Iannaccone, MD, PhD
Sigmund Weitzman, MD |
Tumor
Invasion, Metastasis and Angiogenesis
Kathleen Green, PhD
Jonathan Jones, PhD
Gerald Soff, MD
Mary Sharon Stack, PhD |
Hormones
and Signal
Transduction in Cancer
Mary Hunzicker-Dunn, PhD
Larry Jameson, MD, PhD
V. Craig Jordan, PhD
Chung Lee, PhD
Janardan Reddy, MD
Steven Rosen, MD |
Viral
Carcinogenesis
Laimonis Laimins, PhD
Richard Longnecker, PhD
Kathleen Rundell, PhD
Patricia Spear, PhD
Bayar Thimmapaya, PhD |
Applicants
must be U.S. citizens or permanent residents who are completing
their residency or who have completed one year in an accredited
fellowship program.
For additional
information about the Division
of Hematology/Oncology
For additional
information about the laboratory
preceptors
Applicants
should send their curriculum vitae, medical school transcripts,
statement of research interests, list of three potential mentors
and three letters of reference to:
Robin
Leikin, PhD
Robert H Lurie Comprehensive
Cancer Center
Northwestern University
303 E. Chicago Avenue
Chicago, IL 60611
funded
by the
National Cancer Institute
National Institutes of Health
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Clinical
Trials
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