| You are here: Home: BCU 4|2002: Program Supplement: Sentinel lymph node biopsy
| Sentinel
Lymph Node Biopsy (SLNB) |
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| Miami meeting attendees:
What technique do you utilize in performing sentinel
lymph node biopsies?
Is SLNB a good option for a woman with a 2 cm lesion
high in the upper-outer quadrant in the tail of Spence?
Have you done SLNB in a woman with DCIS?
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Sentinel lymph node biopsy (SLNB) has been shown to be accurate
using a variety of techniques and a variety of dyes and tracers.
Most surgeons performing sentinel node biopsies utilize both dye
and radioisotopes to identify the sentinel node. Overall, surgeons
report that about two-thirds of the SLNBs performed are negative,
sparing the patient the need for axillary dissection.
SLNB is now being utilized in some patients with DCIS and more
than one-third of surgeons have done an SLNB in a DCIS patient.
Cox CE. Lymphatic mapping in breast cancer: Combination technique.
Ann Surg Oncol 2001; 8 ( 9 Suppl):67S-70S. Abstract
Derossis AM et al. A trend analysis of the relative value of
blue dye and isotope localization in 2,000 consecutive cases of
sentinel node biopsy for breast cancer. J Am Coll
Surg 2001; 193 ( 5 ) : 4 7 3 - 8 . Abstract
Hansen NM. Blue versus hot: Learning the techniques with dye
and isotopes. Ann Surg Oncol 2001;8(9 Suppl):64S-66S.
Abstract
Lucci A Jr et al. National practice patterns of sentinel lymph
node dissection for breast carcinoma. J Am Coll Surg
2001;192(4):453-8. Abstract
| When
Is Sentinel Lymph Node Biopsy (SLNB) Appropriate? |
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| Miami meeting attendees:
Is SLNB currently the standard of care for patients
with clinical T1NO disease?
Is SLNB useful after neoadjuvant chemotherapy?
Is SLNB a good option for a woman with 2 lesions in
different quadrants
(upper-outer and lower-inner) of the breast?
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More than two-thirds of the surgeons believe that SLNB is now the
standard of care, although both the American College of Surgeons
and the NSABP have current clinical trials addressing this question.
However, there is considerable controversy about the role of SLNB
in several groups of patients, including patients who have undergone
neoadjuvant therapy and those with more than one lesion in the same
breast .
Haid A et al. Is sentinel lymph node biopsy reliable and indicated
after preoperative chemotherapy in patients with breast carcinoma?
Cancer 2001;92:1080-4. Abstract
Julian TB et al. Sentinel lymph node biopsy after neoadjuvant
chemotherapy for breast cancer. Am J Surg 2001;182(4):407-10.
Abstract
Klauber-DeMore N et al. Sentinel lymph node biopsy: Is it indicated
in patients with high-risk ductal carcinoma-in-situ and ductal carcinoma-in-situ
with microinvasion? Ann Surg Oncol 2000;7(9):636-42.
Abstract
Pendas S et al. Sentinel node biopsy in ductal carcinoma in
situ patients. Ann Surg Oncol 2000 ; 7 : 15-20. Abstract
Stearns V et al. Sentinel lymphadenectomy after neoadjuvant
chemotherapy for breast cancer may reliably represent the axilla
except for inflammatory breast cancer. Ann Surg Oncol 2002;9(3):235-42.
Abstract
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