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Postmastectomy Radiation Therapy

Would you recommend postmastectomy radiation therapy for the following patients with 4.2 cm tumors? (percent answering yes)


The 2000 NIH Consensus Conference and the NCCN guidelines indicate that postmastectomy radiation therapy is standard for women with four or more positive axillary lymph nodes. A small but significant fraction of physicians do not follow this practice, and many respondents indicate that they recommend radiation therapy for women with three positive nodes. Age does not seem to be an important factor in this decision. Patients with one to three positive nodes are currently being studied in a large Interg roup randomized clinical trial.

Arriagada R. Radiotherapy for breast cancer. N Engl J Med 2002; 346 ( 11):862-4. Abstract

Hurkmans CW et al. Reduction of cardiac and lung complication probabilities after breast
irradiation using conformal radiotherapy with or without intensity modulation.
Radiother Oncol 2002;62(2):163-71. Abstract

Pierce LJ. Treatment guidelines and techniques in delivery of postmastectomy radiotherapy in management of operable breast cancer. J Natl Cancer Inst Monogr 2001;30:117-124. Abstract

Recht Aet al. Postmastectomy radiotherapy: Clinical practice guidelines of the American Society of Clinical Oncology. J Clin Oncol 2001;19(5):1539-69. Abstract

Vallis KA et al. Assessment of coronary heart disease morbidity and mortality after radiation
therapy for early breast cancer.
J Clin Oncol 2002;20(4):1036-42. Abstract

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PROGRAM SUPPLEMENT
Editor's Note
Local and systemic therapy of DCIS
Adjuvant systemic therapy
Neoadjuvant systemic therapy
Treatment of metastatic disease
Management of patients with HER2-positive disease
Sentinel lymph node biopsy
Postmastectomy radiation therapy
Breast reconstruction
Local recurrence
Other topics
Tumor board cases
 
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