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Baselga J et al. HER2 overexpression and paclitaxel sensitivity in breast cancer: Therapeutic implications. Oncology 1997;11(3 Suppl 2):43-8. Abstract

Loesch D et al. Phase II multicenter trial of a weekly paclitaxel and carboplatin regimen in patients with advanced breast cancer. J Clin Oncol 2002;20:3857-64. Abstract

Pegram MD et al. Trastuzumab and chemotherapeutics: Drug interactions and synergies. Semin Oncol 2000;27(6 Suppl 11):21-5. Abstract

Pegram MD et al. The effect of HER-2/neu overexpression on chemotherapeutic drug sensitivity in human breast and ovarian cancer cells. Oncogene 1997;15(5):537-47. Abstract

Perez EA et al. A phase II study of paclitaxel plus carboplatin as first-line chemotherapy for women with metastatic breast carcinoma. Cancer 2000;88:124-31. Abstract

Robert N et al. Randomized phase III study of trastuzumab, paclitaxel, and carboplatin versus trastuzumab and paclitaxel in women with HER-2 overexpressing metastatic breast cancer: An update including survival. J Clin Oncol 2004;22(14 Suppl);Abstract 573.

Rowland KM et al. NCCTG 98-32-52:Randomized phase II trial of weekly versus every 3-week administration of paclitaxel, carboplatin and trastuzumab in women with HER2 positive metastatic breast cancer (MBC). Proc ASCO 2003;Abstract 31.

Seidman A et al. Cardiac dysfunction in the trastuzumab clinical trials experience. J Clin Oncol 2002;20:1215-21. Abstract

Slamon DJ et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 2001;344(11):783-92. Abstract

 

Baum M et al. Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early-stage breast cancer: Results of the ATAC (Arimidex, Tamoxifen Alone or in Combination) trial efficacy and safety update analyses. Cancer 2003;98:1802-1810. Abstract

Boccardo F et al. Anastrozole appears to be superior to tamoxifen in women already receiving adjuvant tamoxifen treatment. Breast Cancer Res Treat 2003;82;Abstract 3.

Coombes RC et al. A randomized trial of exemestane after two to three years of tamoxifen therapy in postmenopausal women with primary breast cancer. N Engl J Med 2004;350:1081-92. Abstract

Goss PE et al. A randomized trial of letrozole in postmenopausal women after five years of tamoxifen therapy for early-stage breast cancer. N Engl J Med 2003;349:1793-802. Abstract

Jakesz R, on behalf of the ABCSG, the GABG. Benefits of switching postmenopausal women with hormone-sensitive early breast cancer to anastrozole after 2 years adjuvant tamoxifen: combined results from 3,123 women enrolled in the ABCSG Trial 8 and the ARNO 95 trial. Presentation. San Antonio Breast Cancer Symposium 2004. Abstract 2

Winer EP et al. American Society of Clinical Oncology technology assessment on the use of aromatase inhibitors as adjuvant therapy for postmenopausal women with hormone receptorpositive breast cancer: Status report 2004. J Clin Oncol 2005;23(3):619-29. Abstract

Howell A, on behalf of the ATAC Trialists’ Group. The ATAC (‘Arimidex’, Tamoxifen, alone or in Combination) trial in postmenopausal women with early breast cancer-updated efficacy results based on a median follow of 5 years. Presentation. San Antonio Breast Cancer Symposium 2004. Abstract

 
 
 
     
 
 

 
Editor’s Note:
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Joyce O’Shaughnessy, MD
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Charles E Geyer Jr, MD
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Raimund V Jakesz, MD
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Soonmyung Paik, MD
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