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Capecitabine: Recent publications

Ahn Sr, JH et al. Phase II study of a combination chemotherapy of capecitabine and vinorelbine in metastatic breast cancer with previous exposure to anthracycline and taxane: Preliminary results. Proc ASCO 2002;Abstract 2030.

Blum JL. The role of capecitabine, an oral, enzymatically activated fluoropyrimidine, in the treatment of metastatic breast cancer. Oncologist 2001;6(1):56-64. Abstract

Cassata A et al. Capecitabine: Indications and future perspectives in the treatment of metastatic colorectal and breast cancer. Tumori 2001;87(6):364-71. Abstract

Chan SC et al. A phase II study on an all-oral regimen of capecitabine (XelodaTM) (X), idarubicin (I) and cyclophosphamide (C) (XIC) for metastatic breast cancer - safety, efficacy and quality of life. Proc ASCO 2002;Abstract 2023.

Cunningham D, Coleman R. New options for outpatient chemotherapy — the role of oral fluoropyrimidines. Cancer Treat Rev 2001;27(4):211-20. Abstract

Donaldson LA et al. A phase I/II study of carboplatin, vinorelbine and capecitabine in patients with metastatic breast cancer. Proc ASCO 2002;Abstract 1960.

Fujimoto-Ouchi K et al. Antitumor activity of combinations of anti-HER-2 antibody trastuzumab and oral fluoropyrimidines capecitabine/5'-dFUrd in human breast cancer models. Cancer Chemother Pharmacol 2002;49(3):211-6. Abstract

Fujimoto-Ouchi K et al. Schedule dependency of antitumor activity in combination therapy with capecitabine/5'-deoxy-5-fluorouridine and docetaxel in breast cancer models. Clin Cancer Res 2001;7(4):1079-86. Abstract

Fumoleau P et al. Capecitabine (Xeloda) in patients with advanced breast cancer (ABC), previously treated with anthracyclines and taxanes: Results of a large phase II study. Proc ASCO 2002;Abstract 247.

Ghosn M et al. Vinorelbine (Navelbine) IV and capecitabine (vinocap) as front line chemotherapy in metastatic breast cancer (MBC). Proc ASCO 2002;Abstract 1978.

Gradishar WJ. Clinical status of capecitabine in the treatment of breast cancer. Oncology (Huntingt) 2001;15(1 Suppl 2):69-71;discussion 72. Abstract

Hess DD et al. Phase I - II trial of capecitabine and vinorelbine in elderly patients (pts: > 65 y) with metastatic breast cancer (MBC): SAKK 25 / 99 for the Swiss Group of Clinical Cancer Research, Berne, Switzerland. Proc ASCO 2002;Abstract 2915.

Hori T et al. A randomized study comparing oral and standard regimens for metastatic breast cancer. Oncol Rep 2001;8(5):1067-71. Abstract

Hwang JJ, Marshall JL. Capecitabine: Fulfilling the promise of oral chemotherapy. Expert Opin Pharmacother 2002;3(6):733-43. Abstract

Maher JF, Villalona-Calero MA. Taxanes and capecitabine in combination: Rationale and clinical results. Clin Breast Cancer 2002;2(4):287-93. Abstract

O'Shaughnessy J. Clinical experience of capecitabine in metastatic breast cancer. Eur J Cancer 2002;38 Suppl 2:10-4. Abstract

O'Shaughnessy J et al. Superior survival with capecitabine plus docetaxel combination therapy in anthracycline-pretreated patients with advanced breast cancer: Phase III trial results. J Clin Oncol 2002;20(12):2812-23. Abstract

O'Shaughnessy JA et al. Randomized, open-label, phase II trial of oral capecitabine (Xeloda®) vs a reference arm of intravenous CMF (cyclophosphamide, methotrexate and 5-fluorouracil) as first-line therapy for advanced/metastatic breast cancer. Ann Oncol 2001;12:1247-54. Abstract

Semiglazov TY et al. Oral capecitabine (Xeloda) in the treatment of anthracycline-refractory, anthracycline and docetaxel-refractory metastatic breast cancer (MBC). Proc ASCO 2002;Abstract 2061.

Talbot DC et al. Randomised, phase II trial comparing oral capecitabine (Xeloda) with paclitaxel in patients with metastatic/advanced breast cancer pretreated with anthracyclines. Br J Cancer 2002;86:1367-72. Abstract

Twelves C. Vision of the future: Capecitabine. Oncologist 2001;6 Suppl 4:35-9. Abstract

 

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Joyce O'Shaughnessy, MD
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Daniel F Hayes, MD
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Melody A Cobleigh, MD
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John F Robertson, MD, FRCS
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