CONTENT VALIDATION AND DISCLOSURES

Research To Practice is committed to providing its participants with high-quality, unbiased and state-of-the-art education. We assess potential conflicts of interest with faculty, planners and managers of CME activities. Real or apparent conflicts of interest are identified and resolved by a peer review content validation process. The content of each activity is reviewed by both a member of the scientific staff and an external independent reviewer for fair balance, scientific objectivity of studies referenced and patient care recommendations.

The scientific staff and consultants for Research To Practice are involved in the development and review of content for educational activities and report the following real or apparent conflicts of interest for themselves (or their spouses/partners) that have been resolved through a peer review process: Richard Kaderman, PhD, Neil Love, MD, Douglas Paley, Michelle Paley, MD, Margaret Peng, Lilliam Sklaver Poltorack, PharmD, Chris Thomson, MD, MS and Kathryn Ault Ziel, PhD — no real or apparent conflicts of interest to report; Sally Bogert, RNC, WHCNP — shareholder of Amgen Inc. Research To Practice receives education grants from Abraxis Oncology, Amgen Inc, AstraZeneca Pharmaceuticals LP, Bayer Pharmaceuticals Corporation/Onyx Pharmaceuticals Inc, Biogen Idec, Genentech BioOncology, Genomic Health Inc, Roche Laboratories Inc and Sanofi-Aventis, who have no influence on the content development of our educational activities.

In addition, the following faculty (and their spouses/partners) have reported real or apparent conflicts of interest that have been resolved through a peer review process:

Dr Burstein — Speakers Bureau: Amgen Inc, Genentech BioOncology. Dr Buzdar — Consulting Fees: AstraZeneca Pharmaceuticals LP, Genentech BioOncology, Pfizer Inc, Roche Laboratories Inc; Contracted Research: AstraZeneca Pharmaceuticals LP, Genentech BioOncology, Pfizer Inc, Roche Laboratories Inc, Taiho Pharmaceutical Co Ltd. Dr Hayes — No financial interests or affiliations to disclose. Dr Hudis — Consulting Fees: Amgen Inc, AstraZeneca Pharmaceuticals LP, Bristol-Myers Squibb Company, Eli Lilly and Company, Genentech BioOncology, Novartis Pharmaceuticals, Pfizer Inc, Roche Laboratories Inc, Sanofi-Aventis; Fees for Non- CME Services Directly from Commercial Interests or Their Agents: AstraZeneca Pharmaceuticals LP, Roche Laboratories Inc, Sanofi-Aventis; Contracted Research: Amgen Inc, AstraZeneca Pharmaceuticals LP, Bristol-Myers Squibb Company, Eli Lilly and Company, Genentech BioOncology, Kosan Biosciences, Novartis Pharmaceuticals, Pfizer Inc, Roche Laboratories Inc, Sanofi-Aventis; Ownership Interest: Genomic Health Inc. Dr Miller — Consulting Fees: Genentech BioOncology, Roche Laboratories Inc; Fees for Non-CME Services Directly from Commercial Interests or Their Agents: Genentech BioOncology, Roche Laboratories Inc; Contracted Research: AstraZeneca Pharmaceuticals LP, Genentech BioOncology, Roche Laboratories Inc, Sanofi-Aventis. Dr Osborne — Royalty: Lippincott Williams & Wilkins; Consulting Fees: Pfizer Inc; Contracted Research: AstraZeneca Pharmaceuticals LP. Dr Pegram — Consulting Fees: AstraZeneca Pharmaceuticals LP, Genentech BioOncology, Sanofi-Aventis. Dr Ravdin — Consulting Fees: AstraZeneca Pharmaceuticals LP, Sanofi-Aventis; Ownership Interest: Adjuvant! Inc. Dr Robertson — Consulting Fees: AstraZeneca Pharmaceuticals LP, Novartis Pharmaceuticals, Pfizer Inc, Schering AG; Fees for Non-CME Services Received Directly from Commercial Interest or Their Agents: AstraZeneca Pharmaceuticals LP, Novartis Pharmaceuticals, Pfizer Inc; Contracted Research: AstraZeneca Pharmaceuticals LP, Novartis Pharmaceuticals, Schering AG. Dr Sledge — Consulting Fees: Genentech BioOncology, Roche Laboratories Inc; Contracted Research: Sanofi-Aventis. Dr Vogel — Consulting Fees: Amgen Inc, AstraZeneca Pharmaceuticals LP, Biomira Inc, Cancer International Research Group (BCIRG), Genentech BioOncology, GlaxoSmithKline, Ortho Biotech Products LP, Pfizer Inc, Sanofi-Aventis, Tibotec Inc; Speakers Bureau: Amgen Inc, AstraZeneca Pharmaceuticals LP, Biomira Inc, Bristol-Myers Squibb Company, Eli Lilly and Company, Genentech BioOncology, GlaxoSmithKline, Novartis Pharmaceuticals, Ortho Biotech Products LP, Pfizer Inc, Pierre-Fabre Pharmaceutical Inc, Roche Laboratories Inc, Sanofi-Aventis, Tibotec Inc; Contracted Research: Amgen Inc, AstraZeneca Pharmaceuticals LP, Biomira Inc, Bristol-Myers Squibb Company, Cancer International Research Group (BCIRG), Eisai Inc, Eli Lilly and Company, Genentech BioOncology, GlaxoSmithKline, Novartis Pharmaceuticals, NSABP, Ortho Biotech Products LP, Pfizer Inc, Roche Laboratories Inc, Sanofi-Aventis, Taiho Pharmaceutical Co Ltd, Tibotec Inc. Dr Winer — Consulting Fees: AstraZeneca Pharmaceuticals LP, Genentech BioOncology, Genomic Health Inc, Roche Laboratories Inc, Sanofi-Aventis; Fees for Non-CME Services Received Directly from Commercial Interest or Their Agents: Genomic Health Inc; Contracted Research: AstraZeneca Pharmaceuticals LP, Genentech BioOncology, Roche Laboratories Inc, Sanofi-Aventis.

This educational activity contains discussion of published and/or investigational uses of agents that are not indicated by the Food and Drug Administration. Research To Practice does not recommend the use of any agent outside of the labeled indications. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications and warnings. The opinions expressed are those of the presenters and are not to be construed as those of the publisher or grantors.