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Adjuvant use of aromatase inhibitors for postmenopausal, ER-positive patients

Pharmacokinetics of anastrozole and tamoxifen alone and in combination during adjuvant endocrine therapy for early breast cancer in postmenopausal women: A subprotocol of the "Arimidex® and Tamoxifen Alone or in Combination" (ATAC) trial. Br J Cancer 2001;85(3):317-324. Abstract

Baum M. The ATAC (Arimidex, Tamoxifen, Alone or in Combination) adjuvant breast cancer trial in postmenopausal women. Breast Cancer Res Treat 2001;69(3):Abstract 8.

Baum M et al. Sequential power calculations in a recruitment phase of a multicentre trial — the experience of the 'Arimidex (anastrozole), tamoxifen alone or in combination' (ATAC) study. Proc ASCO 2002;Abstract 185.

Brodie A. Aromatase inhibitors in breast cancer. Trends Endocr Metab 2002;13(2):61-65. Abstract

Buzdar AU. Anastrozole (Arimidex) —- an aromatase inhibitor for the adjuvant setting? Br J Cancer 2001;85(2 suppl):6-10. Abstract

Duffy SRG et al. The ATAC ('Arimidex,' tamoxifen, alone or in combination) early breast cancer (EBC) trial in postmenopausal (PM) patients: Endometrial subprotocol results. Proc ASCO 2002;Abstract 158.

Fallowfield L et al. Assessing the quality of life (QOL) of postmenopausal (PM) women randomized into the ATAC ('Arimidex,' tamoxifen, alone or in combination) adjuvant breast cancer (BC) trial. Proc ASCO 2002;Abstract 159.

Goss PE. Preliminary data from ongoing adjuvant aromatase inhibitor trials. Clin Cancer Res 2001;7(12 suppl):4397s-4401s. Abstract

Howell A. Future use of selective estrogen receptor modulators and aromatase inhibitors. Clin Cancer Res 2001;7(12 suppl):4402s-4410s. Abstract

Howell A et al. Where do selective estrogen receptor modulators (SERMs) and aromatase inhibitors (AIs) now fit into breast cancer treatment algorithms?J Steroid Biochem Mol Biol 2001;79:227-237. Abstract

Ingle JN. Aromatase inhibition and antiestrogen therapy in early breast cancer treatment and chemoprevention. Oncology (Huntingt) 2001;15:28-34. Abstract

Johnson PE, Buzdar A. Are differences in the available aromatase inhibitors and inactivators significant? Clin Cancer Res 2001;7(12 Suppl):4360s-4368s. Abstract

Mamounas EP. Adjuvant exemestane therapy after 5 years of tamoxifen: Rationale for the NSABP B-33 trial. Oncology (Huntingt) 2001;15(5 Suppl 7):35-39. Abstract

Nicholls H. Aromatase inhibitors continue their ATAC on tamoxifen. Trends Mol Med 2002;8(4):S12-3. Abstract

Ragaz J. Adjuvant trials of aromatase inhibitors: Determining the future landscape of adjuvant endocrine therapy. J Steroid Biochem Mol Biol 2001;79:133-141. Abstract

Menopause and the endocrine effects of adjuvant therapy on pre- and postmenopausal patients

Bhatavdekar JM et al. Endocrine function in premenopausal and postmenopausal advanced breast cancer patients treated with CMF or tamoxifen. Neoplasma 1992;39:123-7. Abstract

Bianco AR et al. Prognostic role of amenorrhea induced by adjuvant chemotherapy in premenopausal patients with early breast cancer. Br J Cancer 1991;63:799-803. Abstract

Bines J et al. Ovarian function in premenopausal women treated with adjuvant chemotherapy for breast cancer. J Clin Oncol 1996;14:1718-29. Abstract

Braverman AS et al. Premenopausal serum estradiol (E2) levels may persist after chemotherapy (CT)- induced amenorrhea in breast cancer (BC). Proc ASCO 2002;Abstract 164.

Burger HG. The endocrinology of the menopause. J Steroid Biochem Mol Biol 1999;69(1-6):31-5. Abstract

Burger HG. The menopause: When it is all over or is it? Aust N Z J Obstet Gynaecol 1994;34(3):293-5. Abstract

Burger HG et al. Hormonal changes in the menopause transition. Recent Prog Horm Res 2002;57:257- 75. Abstract

Burger HG et al. Prospectively measured levels of serum follicle-stimulating hormone, estradiol, and the dimeric inhibins during the menopausal transition in a population-based cohort of women. J Clin Endocrinol Metab 1999;84(11):4025-30. Abstract

Chakravarti S et al. Hormonal profiles after the menopause. Br Med J 1976;2(6039):784-7. Abstract

Collichio F, Pandya K. Amenorrhea following chemotherapy for breast cancer: Effect on disease-free survival. Oncology (Huntingt) 1994;8:45-52. Abstract

Del Mastro L et al. Amenorrhea induced by adjuvant chemotherapy in early breast cancer patients: Prognostic role and clinical implications. Breast Cancer Res Treat 1997;43:183-90. Abstract

Goldhirsch A et al. The magnitude of endocrine effects of adjuvant chemotherapy for premenopausal breast cancer patients. The International Breast Cancer Study Group. Ann Oncol 1990;1:183-8. Abstract

Johannes CB, Crawford SL. Menstrual bleeding, hormones, and the menopausal transition. Semin Reprod Endocrinol 1999;17(4):299-309. Abstract

Kalantaridou SN, Nelson LM. Premature ovarian failure is not premature menopause. Ann N Y Acad Sci 2000;900:393-402. Abstract

Lower EE et al. The risk of premature menopause induced by chemotherapy for early breast cancer. J Womens Health Gend Based Med 1999;8:949-54. Abstract

Pagani O et al. Prognostic impact of amenorrhoea after adjuvant chemotherapy in premenopausal breast cancer patients with axillary node involvement: Results of the International Breast Cancer Study Group (IBCSG) Trial VI. Eur J Cancer 1998;34:632-40. Abstract

Poikonen P et al. Prognostic effect of amenorrhoea and elevated serum gonadotropin levels induced by adjuvant chemotherapy in premenopausal node-positive breast cancer patients. Eur J Cancer 2000;36:43-8. Abstract

Sherman BM et al. The menopausal transition: Analysis of LH, FSH, estradiol, and progesterone concentrations during menstrual cycles of older women. J Clin Endocrinol Metab 1976;42(4):629-36. Abstract

Toma S et al. Chemotherapy-induced amenorrhea and other clinical and pathological parameters in the prognosis of breast cancer patients. J Chemother 1992;4:321-5. Abstract

Utian WH. Ovarian function, therapy-oriented definition of menopause and climacteric. Exp Gerontol 1994;29(3-4):245-51. Abstract

 

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Editor's Note
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George W Sledge, Jr, MD
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Anthony Howell, BSc, MBBS, MSc, FRCP
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I Craig Henderson, MD
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Eleftherios P Mamounas, MD
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