American Society of Breast Surgeons Annual Meeting 2008

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The Role of the Surgeon in the Interdisciplinary Management of Early Breast Cancer
A Continuing Medical Education Audio Series

OVERVIEW OF ACTIVITY/TARGET AUDIENCE

Historically, surgery has represented the primary method for treating breast cancer. More recently, however, the diagnostic, surgical and medical management of breast malignancies has escalated in complexity due to advancements and availability of novel technology, pharmaceuticals and clinical experience. Thus, the direction of breast cancer care has evolved toward a multifaceted approach necessitating the input from a variety of multidisciplinary experts. This paradigm shift has created the opportunity for extensive knowledge exchange among interrelated oncologic subspecialties, and the challenge of ensuring major clinical advances influencing the selection of local and systemic breast cancer treatment algorithms are effectively disseminated among all multidisciplinary team members. To bridge the gap between research and patient care, this CME activity utilizes one-on-one interviews and a panel discussion with leading breast cancer investigators. By providing access to the latest research developments and expert perspectives, this program assists breast surgeons in the formulation of up-to-date clinical management strategies.

LEARNING OBJECTIVES

Compare management strategies of community-based general surgeons and breast cancer surgical specialists for the treatment of early breast cancer, and apply relevant information to clinical practice.
Evaluate issues related to the accuracy, reliability and interpretation of the ER and HER2 status of breast tumors, in the context of local laboratory practices and national guidelines.
Identify the rationale for and benefits of extended adjuvant endocrine therapy, and utilize this approach for patients with hormone receptor-positive breast cancer.
Describe the evidence-based risks and benefits of adjuvant trastuzumab therapy, and implement a plan for the initial treatment for patients with HER2-positive early breast cancer.
Evaluate the utility of tissue-based genomic assays for therapeutic decision-making and, when applicable, use these in the selection of individualized treatment regimens for patients with early breast cancer.
Review emerging research data evaluating the utility and long-term impact of sentinel lymph node biopsy, and translate these findings to current practice.
Discuss the risks and benefits of partial breast irradiation and the clinical trials evaluating this technique with appropriately selected patients.
Utilize magnetic resonance imaging in appropriately selected patients with breast cancer.

ACCREDITATION STATEMENT

Research To Practice is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

CREDIT DESIGNATION STATEMENT

Research To Practice designates this educational activity for a maximum of 3.75 AMA PRA Category 1 Credit(s)™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

HOW TO USE THIS CME ACTIVITY

This CME activity contains both audio and print components. To receive credit, the participant should listen to the CDs, review the Internet content and complete the Post-test and Educational Assessment located BreastCancerUpdate.com/ Surgeons. This monograph contains edited comments, clinical trial schemas, graphics and references that supplement the audio program. BreastCancerUpdate.com/Surgeons includes an easy-to-use, interactive version of this monograph with links to relevant full-text articles, abstracts, trial information and other web resources indicated here in blue underlined text.

This program is supported by educational grants from Genentech BioOncology, Genomic Health Inc and Novartis Pharmaceuticals Corporation.

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