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1Boccardo F. Presentation. San Antonio Breast Cancer Symposium, 2003. 2Boccardo F et al. Anastrozole appears to be superior to tamoxifen in women already receiving adjuvant tamoxifen treatment. Breast Cancer Res Treat 2003;82(Suppl1); Abstract 3 .

Cauley JA et al. Continued breast cancer risk reduction in postmenopausal women treated with raloxifene: 4-year resultsfromtheMOREtrial. Multiple outcomes of raloxifene evaluation. Breast Cancer ResTreat 2001;65(2):125-34. Abstract

Coombes RC et al. A randomized trial of exemestane after two to three years of tamoxifen therapy in postmenopausal women with primary breast cancer. N Engl J Med 2004;350(11):1081-92. Abstract

Gnant M et al. Changes in bone mineral density caused by anastrozole or tamoxifen in combination with goserelin (± zoledronate) as adjuvant treatment for hormone receptor-positive premenopausal breast cancer: results of a randomized multicenter trial. Breast Cancer Res Treat 2002; Abstract 12.

Goss PE et al. A randomized trial of letrozole in postmenopausal women after five years of tamoxifen therapy for early-stage breast cancer. N Engl JMed 2003;349(19):1793-802. Abstract

Howell A et al. Effect of anastrozole on bone mineral density: 2-year results of the 'arimidex' (anastrozole), tamoxifen, alone or in combination (ATAC) trial. Breast Cancer Res Treat 2003; . Abstract 129

Locker GY et al. The time course of bone fractures observed in the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial. Proc ASCO 2003; Abstract 98 .

O'Regan RM et al. Effects of raloxifene after tamoxifen on breast and endometrial tumor growth in athymic mice. J Natl CancerInst 2002;94(4):274-83. Abstract

 

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Editor's Note
 

Case 1: A 62-year-old woman with ER/PR-positive, HER2-negative, nodenegative multicentric breast cancer (from the practice of Thomas Cartwright, MD)

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Case 2: A 54-year-old woman seven years after node-positive (6/18),ER-positive, PR-negative infiltrating ductal carcinoma with osteoporosis and postchemotherapy pancytopenia (from the practice of AllanFreedman, MD)
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Case 3: A 79-year-old woman with ER-positive, PR-negative, HER2-negative metastatic lobular breast cancer and malignant ascites (from the practice of Steven Weiss, MD)
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Case 4: A 79-year-old woman presenting with a palpable five-centimeter nodepositive (7/10), ER/PR-positive lobular carcinoma (from the practice of Howard Abel, MD)
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Case 5: A 35-year-old woman with a strong family history of breast cancer with comedo DCIS followed by an infiltrating ductal carcinoma three years later (from the practice of Stephen Grabelsky, MD)
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Case 6: A 39-year-old woman presenting with locally advanced breast cancer and diffuse bony metastases (from the practice of Rajesh Bajaj, MD)
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Case 7: A 70-year-old woman with ER-positive, HER2-negative metastatic lobular carcinoma in the bone, liver and soft tissue of the orbit (from the practice of Richard Levine, MD)
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