You are here: BCU: Her2 Testing in Breast Cancer Management: Concordance of HER2 Status Between Primary and Metastatic Lesions  

Cardoso F et al. Evaluation of HER2, p53, bcl-2, topoisomerase II-alpha, heat shock proteins 27 and 70 in primary breast cancer and metastatic ipsilateral axillary lymph nodes. Ann Oncol 2001;12(5):615-20. Abstract.

Dittadi R et al. Evaluation of HER-2/neu in serum and tissue of primary and metastatic breast cancer patients using an automated enzyme immunoassay. Int J Biol Markers 2001;16(4):255-61. Abstract.

Masood S, Bui MM. Assessment of Her-2/neu overexpression in primary breast cancers and their metastatic lesions: An immunohistochemical study. Ann Clin Lab Sci 2000;30(3):259-65. Abstract.

Niehans GA et al. Stability of HER-2/neu expression over time and at multiple metastatic sites. J Natl Cancer Inst 1993;85(15):1230-5. Abstract.

Sekido Y et al. Heterogeneous gene alterations in primary breast cancer contribute to discordance between primary and asynchronous metastatic/recurrent sites: HER2 gene amplification and p53 mutation. Int J Oncol 2003;22(6):1225-32. Abstract.

Simon R et al. Patterns of her-2/neu amplification and overexpression in primary and metastatic breast cancer. J Natl Cancer Inst 2001;93(15):1141-6. Abstract.

Tanner M et al. Amplification of HER-2/neu and topoisomerase IIalpha in primary and metastatic breast cancer. Cancer Res 2001;61(14):5345-8. Abstract.

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Concordance Between Local and Central Laboratory HER2 Testing
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Comparison of HER2 Assays
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Concordance of HER2 Status Between Primary and Metastatic Lesions
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College of American Pathologists
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