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Anastrozole, Tamoxifen, Alone or in Combination (ATAC Trial)

ATAC Trialists’ Group. Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: First results of the ATAC randomised trial. Lancet 2002;359:2131-2139. Abstract

Baum M. The ATAC (Arimidex, Tamoxifen, Alone or in Combination) adjuvant breast cancer trial in postmenopausal patients: Factors influencing the success of patient recruitment. Eur J Cancer 2002;38:1984–1986. Abstract

Buzdar A. Anastrozole as Adjuvant Therapy for Early-Stage Breast Cancer: Implications of the ATAC Trial. Clin Breast Cancer 2003;4 Suppl 1:S42-8. Abstract

Buzdar A et al. The ATAC ('Arimidex', Tamoxifen, Alone or in Combination) trial in postmenopausal women with early breast cancer — Updated efficacy results based on a median follow-up of 47 months. Breast Cancer Res Treat 2002; Abstract 13.

Chung CT, Carlson RW. The role of aromatase inhibitors in early breast cancer. Curr Treat Options Oncol 2003;4(2):133-40. Abstract

Klijn J, for the ATAC Trialists’ Group. The ATAC (anastrozole, Tamoxifen, Alone or in Combination) trial: An efficacy update, focusing on breast cancer (BC) events, based on a median follow-up of 47 months. Proc ASCO 2003:Abstract 338.

Ligibel JA, Winer EP. Clinical differences among the aromatase inhibitors. Clin Cancer Res 2003;9(1 Pt 2):473S-9S. Abstract

Locker GY et al. The time course of bone fractures observed in the ATAC (‘Arimidex’, Tamoxifen, Alone or in Combination) trial. Proc ASCO 2003:Abstract 98.

Sainsbury R on behalf of the ATAC Trialists' Group. Beneficial side-effect profile of anastrozole compared with tamoxifen confirmed by additional 7 months of exposure data: A safety update from the ’Arimidex’, Tamoxifen, Alone or in Combination (ATAC) trial. Breast Cancer Res Treat 2002;Abstract 633.

Winer EP et al. American Society of Clinical Oncology Technology Assessment Working Group Update: Use of aromatase inhibitors in the adjuvant setting. J Clin Oncol 2003;21(13). Abstract

 

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Editor's Note
 
Melvin Silverstein, MD
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Gershon Locker, MD
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Blake Cady, MD, FACS
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Hyman Muss, MD
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