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GYNECOLOGIC ONCOLOGY GROUP (GOG) Web link

The Gynecologic Oncology Group (GOG) is a national organization dedicated to clinical research in the field of gynecologic cancers including cancers that arise from the ovaries, uterus, cervix, vagina and vulva. Its aim is to improve the treatment of gynecologic cancer through research encompassing surgery, radiation therapy, chemotherapy, pathology, immunology and/or gynecologic nursing. GOG consists of over 60 “parent ” institutions, medical schools, colleges and universities and more than 125 affiliated hospitals. There are approximately 45 clinical trials active at any given time.

Contact Information

GOG Statistical and Data Center
Roswell Park Cancer Institute
Elm & Carlton Streets
Buffalo, NY 14263-0001
Phone:(716) 845-5702

GOG Administrative Office
1234 Market Street, Suite 1945
Philadelphia, PA 19107
Phone:(215) 854-0770

NATIONAL CANCER INSTITUTE OF CANADA CLINICAL TRIALS GROUP (NCIC) Web link

The National Cancer Institute of Canada Clinical Trials Group (NCIC CTG) is a cooperative group that conducts clinical trials in cancer therapy and supportive care throughout Canada and internationally. The organization aims to undertake and support research that will lead to reduction in the incidence of and morbidity and mortality from cancer.NCIC established the clinical trials program in 1971 in response to investigators interested in carrying out multicenter trials in Hodgkin’s disease and hypernephroma. The Investigational New Drug (IND) program was established in 1982 and now conducts phase I and II trials with cytotoxics and biologics.New agents from the NCI (US) as well as the pharmaceutical industry are studied.

Open Breast Cancer Protocols

CAN-NCIC-MA20
Phase III Randomized Study of Adjuvant Breast Radiotherapy with or without Regional Radiotherapy in Women with Resected,Early Stage,Invasive Breast Cancer Protocol

CAN-NCIC-MA21; AMGEN-CAN-NCIC-MA21; BMS-CAN-NCIC-MA21; JANSSEN-CAN-NCIC-MA21; P-UPJOHN-CAN-NCIC-MA21
Phase III Randomized Study of Adjuvant Cyclophosphamide, Epirubicin and Fluorouracil Versus Cyclophosphamide, Epirubicin, Filgrastim (G-CSF) and Epoetin Alfa Followed by Paclitaxel Versus Cyclophosphamide and Doxorubicin Followed by Paclitaxel in Premenopausal or Early Postmenopausal Women with Previously Resected Node-Positive or High-Risk Node-Negative Stage I-IIIA Breast Cancer Protocol

CAN-NCIC-MA17; CLB-49805; EORTC-10983; JRF-Vor-Int-10; NCCTG-CAN-MA17; SWOG-CAN-MA17
Phase III Randomized Study of Letrozole Versus Placebo in Women with Primary Breast Cancer Who Have Completed at Least Five Years of Adjuvant Tamoxifen Protocol

Contact Information
Central Office Staff
Queens University
82-84 Barrie Street
Kingston, Ontario
Phone:(613) 533-6430
Dr.Joseph L Pater, Group Director
E-mail:jpater@ctg.queensu.ca

NORTH CENTRAL CANCER TREATMENT GROUP (NCCTG) Web link

The North Central Cancer Treatment Group (NCCTG) conducts clinical trials in the treatment of a wide variety of cancers, as well as studies in the control and prevention of cancer. NCCTG is comprised of approximately 20 community clinics consisting of over 700 physicians and 375 allied-health professionals. Based at the Mayo Cancer Center in Rochester, MN, NCCTG affiliates are located in 11 states and one Canadian province.

Open Breast Cancer Protocols

NCCTG-963255
Phase II Randomized Study of Irinotecan for Refractory Metastatic Breast Cancer Protocol

NCCTG-983252
Phase II Randomized Study of Paclitaxel,Carboplatin and Trastuzumab (Herceptin) as First-Line Chemotherapy in Women with Overexpressed HER2, Metastatic Breast Cancer Protocol

NCCTG-N9932
Phase II Study of Docetaxel and Carboplatin as First-Line Therapy in Patients with Metastatic Adenocarcinoma of the Breast Protocol

NCCTG-N0032
Phase II Study of Fulvestrant (ICI 182780) in Women with Metastatic Breast Cancer Who Have Failed Aromatase Inhibitor Therapy Protocol

NCCTG-N003A
Phase II Study of Oral Vinorelbine in Elderly Women with Stage IV Breast Cancer Protocol

NCCTG-N0031
Phase II Study of Topical Ceramide Cream in Women with Cutaneous Breast Cancer Protocol

NCCTG-N9831;GUMC-00224
Phase III Randomized Study of Doxorubicin Plus Cyclophosphamide Followed by Paclitaxel with or without Trastuzumab (Herceptin) in Patients with HER2 Overexpressing Breast Cancer Protocol

NCCTG-979253;NCI-P98-0133
Phase III Randomized Study of Epoetin Alfa in Anemic Patients with Advanced Cancer Undergoing Chemotherapy Protocol

CAN-NCIC-MA17; CLB-49805; EORTC-10983; JRF-Vor-Int-10; NCCTG-CAN-MA17; SWOG-CAN-MA17
Phase III Randomized Study of Letrozole Versus Placebo in Women with Primary Breast Cancer Who Have Completed at Least Five Years of Adjuvant Tamoxifen Protocol

NCCTG-N9431
Correlation of Menstrual Cycle Phase at the Time of Surgery with Disease- Free Survival in Women with Stage I/II Breast Cancer Protocol

Contact Information
NCCTG Operations Office
Plummer Building
200 1st Street, SW
Rochester, MN 55905
Fax: (507) 284-1902
E-mail: ncctg@mayo.edu

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