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Home: Meeting Highlights: 2001 Interactive Report


Section 3: Sentinel Node Biopsy/Axillary Dissection

17. A 65-year-old woman with a history of adult onset diabetes and obesity (5’8", 190 pounds), has a lumpectomy for a 1.2 cm, ER+ infiltrating ductal carcinoma. Axillary nodes are negative, and she will be treated with radiation therapy to the breast and tamoxifen. At the end of the five years the risk of lymphadema is:

Negligible
About 10%
About 15%
About 25%

7%
40%
34%
19%


Monica Morrow, MD


We know that older age and high body mass index, or obesity, appear to correlate with the risk of lymphedema. I would put this patient’s risk at the end of five years in the 15 to 25 percent range — if you actually look for lymphedema. This highlights a very important issue — physicians greatly underestimate the incidence of lymphedema, because, by and large, it’s not a life-threatening problem. Even when you look at modern series done by expert breast surgeons, patients still develop lymphedema. It’s an unavoidable problem if you dissect the axilla.

18. A patient presents with a 1 centimeter infiltrating ductal breast cancer. Which of the following procedures would you usually recommend?

Sentinel node biopsy
Axillary sampling
Axillary dissection to Level I
Axissection to Level II
Other

61%
4%
7%
24%
4%


19. (For surgeons only): When you do a sentinel node biopsy in a patient with clinically negative nodes along with an excision of the primary lesion, which procedure do you do first?

Sentinel node biopsy
Excision of the primary tumor

78%
22%


Monica Morrow, MD

This is very dependent on the technique used for mapping. With blue dye, you have a big open biopsy cavity, and a lot of the dye will leak back into the cavity. If you’re going to map with blue dye it makes sense to do the sentinel node first. With radioactivity, that may not be so critical, because you’ve let the patient sit for an hour or two anyway, so a substantial amount of the radioactivity has already left the primary tumor site and is in the axilla.

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