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neoadjuvant/adjuvant trastuzumab

Burstein HJ et al. Preoperative Herceptin and paclitaxel (Taxol) for HER2 overexpressing (HER2+) stage II/III breast cancer. Proc ASCO 2001; Abstract 100.

Hortobagyi GN, Perez EA. Integration of trastuzumab into adjuvant systemic therapy of breast cancer: Ongoing and planned clinical trials. Semin Oncol 2001;28:41-6. Abstract

Hurley J et al. Primary therapy with Herceptin, Taxotere and cisplatin in locally advanced and inflammatory breast cancer. Proc ASCO 2001; Abstract 1871.

Leyland-Jones B, Smith I. Role of Herceptin in primary breast cancer: Views from North America and Europe. Oncology 2001;61 Suppl 2:83-91. Abstract

Nabholtz JM, Slamon D. New adjuvant strategies for breast cancer: Meeting the challenge of integrating chemotherapy and trastuzumab (Herceptin). Semin Oncol 2001;28:1-12. Abstract

Nunes RA et al. Serum HER2 in breast cancer patients treated with preoperative therapy with Herceptin and Taxol (H&T). Proc ASCO 2001;Abstract 131.

Paik S, Park C. HER-2 and choice of adjuvant chemotherapy in breast cancer. Semin Oncol 2001;28:332-5. Abstract

Perez EA. The role of adjuvant monoclonal antibody therapy for breast cancer: Rationale and new studies. Curr Oncol Rep 2001;3:516-22. Abstract

Slamon D, Pegram M. Rationale for trastuzumab (Herceptin) in adjuvant breast cancer trials. Semin Oncol 2001;28:13-9. Abstract

Sledge GW et al. Pilot trial of paclitaxel-Herceptin adjuvant therapy for early stage breast cancer (E2198). Breast Cancer Res Treat 2001;Abstract 4.

Sparano JA. Cardiac toxicity of trastuzumab (Herceptin): Implications for the design of adjuvant trials. Semin Oncol 2001;28:20-7. Abstract

concurrent chemotherapy and radiation therapy

Bellon JR et al. Concurrent radiation therapy and paclitaxel or docetaxel chemotherapy in high-risk breast cancer. Int J Radiat Oncol Biol Phys 2000;48:393-7. Abstract

Berg CD, Swain SM. Results of concomitantly administered chemoradiation for locally advanced noninflammatory breast cancer. Semin Radiat Oncol 1994;4:226-235. Abstract

Dubey A et al. Concurrent CMF and radiation therapy for early stage breast cancer: Results of a pilot study. Int J Radiat Oncol Biol Phys 1999;45:877-84. Abstract

Dubey AK et al. Why and how to combine chemotherapy and radiation therapy in breast cancer patients. Recent Results Cancer Res 1998;152:247-54. Abstract

Formenti SC et al. Low HER2/neu gene expression is associated with pathological response to concurrent paclitaxel and radiation therapy in locally advanced breast cancer. Int J Radiat Oncol Biol Phys 2002;52:397-405. Abstract

Formenti SC et al. Concurrent paclitaxel and radiation therapy for breast cancer. Semin Radiat Oncol 1999;9:34-42. Abstract

Hsieh CI et al. Adjuvant sequential chemotherapy with doxorubicin plus cyclophosphamide, methotrexate, and fluorouracil (ACMF) with concurrent radiotherapy in resectable advanced breast cancer. Am J Clin Oncol 2000;23:122-7. Abstract

Leonard CE et al. Does administration of chemotherapy before radiotherapy in breast cancer patients treated with conservative surgery negatively impact local control? J Clin Oncol 1995;13:2906-15. Abstract

Markiewicz DA et al. Concurrent chemotherapy and radiation for breast conservation treatment of early-stage breast cancer. Cancer J Sci Am 1998;4:185-93. Abstract

Markiewicz DA et al. The effects of sequence and type of chemotherapy and radiation therapy on cosmesis and complications after breast conservation therapy. Int J Radiat Oncol Biol Phys 1996;35:661-8. Abstract

Meek AG et al. Concurrent radiochemotherapy in advanced breast cancer. Cancer 1983;51:1001-6. Abstract

Recht A et al. Integration of conservative surgery, radiotherapy, and chemotherapy for the treatment of early-stage, node-positive breast cancer: Sequencing, timing, and outcome. J Clin Oncol 1991;9:1662-7. Abstract

Sauter ER et al. Postmastectomy morbidity after combination preoperative irradiation and chemotherapy for locally advanced breast cancer. World J Surg 1993;17:237-41; discussion 242. Abstract

Serin D et al. Adjuvant combined radiochemotherapy: A feasibility study of a new strategy in stages I and II. Bull Cancer 1997;84:247-53. Abstract

Ung O et al. Combined chemotherapy and radiotherapy for patients with breast cancer and extensive nodal involvement. J Clin Oncol 1995;13:435-43. Abstract

Wallgren A et al. Timing of radiotherapy and chemotherapy following breast-conserving surgery for patients with node-positive breast cancer. International Breast Cancer Study Group. Int J Radiat Oncol Biol Phys 1996;35:649-59. Abstract

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- Harold J Burstein, MD, PhD
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