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  Go to interview with W Sledge Jr, MD
Go to interview with Edward H Romond, MD
Go to interview with Jack Cuzick, PhD
 

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George W Sledge Jr, MD
Professor of Medicine
Ballve-Lantero Professor of Oncology
Indiana University Medical Center
Indianapolis, Indiana

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WMA MP3
Track 1 Introduction by Neil Love, MD
Track 2 Perspectives on the 2005 ASCO meeting
Track 3 Evolution of clinical research with bevacizumab in breast cancer
Track 4 Potential predictors of response to bevacizumab
Track 5 ECOG-E2100: Paclitaxel with or without bevacizumab as first-line therapy for metastatic breast cancer
Track 6 Bevacizumab-associated side effects


Track 7 Progression-free and overall survival observed in E2100
Track 8 Clinical implications of E2100 trial results
Track 9 Bevacizumab in the second- and third-line settings
Track 10 Bevacizumab dosing
Track 11 Nonprotocol use of bevacizumab/capecitabine
Track 12 Future clinical trials with bevacizumab in the adjuvant setting
Track 13 Clinical implications of adjuvant trastuzumab trial results
Track 14 Rates of distant recurrence observed in the combined NCCTG-N9831/NSABP-B-31 analysis
Track 15 Potential benefit of concurrent versus sequential chemotherapy/trastuzumab
Track 16 Adjuvant trastuzumab for patients with node-negative, HER2-positive disease
Track 17 Quality control for HER2 testing
Track 18 Cardiovascular events in carboplatin/docetaxel/trastuzumab arm of BCIRG 006
Track 19 Time course for initiating treatment with adjuvant trastuzumab
Track 20 Perspectives on the cost of newer treatments
Track 21 Cardiac monitoring of patients on adjuvant trastuzumab
Track 22 Personal perspective: A new age of breast cancer management
       
Edward H Romond, MD
Associate Professor of Medicine
Division of Hematology/Oncology
University of Kentucky
Lexington, Kentucky

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Track 1 Introduction by Dr Love
Track 2 Results from combined NCCTG-N9831/NSABP-B-31 analysis
Track 3 Concurrent versus sequential trastuzumab/chemotherapy in the adjuvant setting
Track 4 Potential predictors of trastuzumab-related cardiac toxicity
Track 5 Rationale for including anthracycline-based chemotherapy in NSABP-B-31
Track 6 Strategies to monitor cardiac function in patients receiving adjuvant trastuzumab
Track 7 Discontinuation of adjuvant trastuzumab in patients with decreases in cardiac ejection fraction
Track 8 Counseling patients about the risks and benefits of adjuvant trastuzumab
Track 9 Adjuvant trastuzumab for patients with node-negative disease
Track 10 Duration and time course of adjuvant therapy with trastuzumab
Track 11 Future directions in clinical research with trastuzumab
Track 12 Case discussion: Woman with 25 positive lymph nodes treated on NSABP-B-31
Track 13 Quality control with HER2 testing in community practice
       

Jack Cuzick, PhD
John Snow Professor of Epidemiology
Cancer Research UK Centre for Epidemiology, Mathematics and Statistics
Wolfson Institute of Preventive Medicine
Barts and the London, Queen Mary’s School of Medicine and Dentistry
London, United Kingdom
 
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Track 1 Introduction by Dr Love
Track 2 68-month follow-up data from the ATAC trial
Track 3 Increased incidence of hysterectomy with tamoxifen versus anastrozole in ATAC
Track 4 Rates of bone loss and bone fractures in ATAC


Track 5 Rationale for increased benefit of anastrozole in patients with ER-positive, PR-negative phenotype
Track 6 Reduction in early recurrences with anastrozole
Track 7 Potential benefit of anastrozole versus tamoxifen in ER-positive, HER2-positive disease
Track 8 Switching to an aromatase inhibitor after two to three years of tamoxifen
Track 9 Time course and biologic rationale for breast cancer recurrence
Track 10 Importance of examining optimal duration of adjuvant aromatase inhibitors
Track 11 Design, background and initial results from BIG 1-98
Track 12 Cardiac effects of tamoxifen
Track 13 Risk of cardiovascular disease and aromatase inhibitors
Track 14 Anastrozole as a potential chemopreventative agent
Track 15 Prevention of contralateral tumors in clinical trials of adjuvant aromatase inhibitors
Track 16 Potential antitumor effect of adjuvant bisphosphonates
Track 17 Arthralgias and changes in cognitive function associated with aromatase inhibitors
Track 18 Concordance between estrogen receptor status in primary and secondary breast cancers
Track 19 COX-2 inhibitors and aspirin as potential chemopreventative agents