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Track 1 |
Introduction by Neil Love, MD |
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Track 2 |
Clinical implications of 68-month follow-up data from the ATAC trial |
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Track 3 |
Relative risk reductions in patients with node-negative versus node-positive disease |
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Track 4 |
Impact of all-cause mortality on overall survival in ATAC |
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Track 5 |
Increased rates of hysterectomy with tamoxifen compared to anastrozole |
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Track 6 |
Reduction in early recurrences with anastrozole compared to tamoxifen |
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Track 7 |
Potential benefits of neoadjuvant endocrine therapy |
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Track 8 |
Side effects observed in ATAC |
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Track 9 |
Anastrozole-related arthralgias |
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Track 10 |
Benefit of anastrozole in patients with ER-positive, PR-negative phenotype |
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Track 11 |
Switching from tamoxifen to an aromatase inhibitor after two to three years |
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Track 12 |
Initiation of an aromatase inhibitor after five years of adjuvant tamoxifen |
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Track 13 |
Tailoring breast cancer therapy to vulnerable time points |
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Track 14 |
Theoretical rationale for the “carryover effect” of adjuvant hormonal therapy |
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Track 15 |
Austrian trial (ABCSG-12) of LHRH agonist with tamoxifen or anastrozole with or without zoledronic acid |
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Track 16 |
Nonprotocol use of ovarian ablation and an aromatase inhibitor for premenopausal women with ER-positive, PR-positive disease |
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Track 17 |
TARGIT trial of targeted intraoperative radiation therapy |
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Track 18 |
Risks and benefits of partial breast irradiation techniques |
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Track 1 |
Introduction by Dr Love |
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Track 2 |
US Oncology adjuvant trial (01062): AC followed by docetaxel with or without capecitabine |
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Track 3 |
Tolerability of capecitabine in combination with paclitaxel |
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Track 4 |
Combination versus sequential single-agent chemotherapy in the metastatic setting |
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Track 5 |
Capecitabine plus trastuzumab as first-line therapy for HER2-positive metastatic disease |
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Track 6 |
Poor prognosis of patients with ER-negative, PR-negative, HER2-negative disease |
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Track 7 |
Individualizing treatment based on time course and response to other therapies |
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Track 8 |
Evolution of clinical research with nanoparticle paclitaxel (ABI-007) |
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Track 9 |
Tolerability and efficacy of ABI-007 |
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Track 10 |
Potential role of ABI-007 in clinical practice |
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Track 11 |
Gemcitabine/paclitaxel in patients with metastatic disease |
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Track 12 |
Advantage of avoiding premedication with ABI-007 |
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Track 13 |
Nonprotocol adjuvant chemotherapeutic regimen for patients with node-positive disease |
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Track 14 |
Adjuvant taxanes for patients with node-negative disease |
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Track 15 |
Up-front adjuvant hormonal therapy for postmenopausal patients |
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Track 16 |
Nonprotocol management of premenopausal patients with high-risk ER-positive disease |
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Track 17 |
Phase II trial of capecitabine/paclitaxel for patients with metastatic breast cancer |
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John R Mackey, MD
Medical Oncologist, Cross Cancer Institute
Associate Professor, Medical and Experimental Oncology University of Alberta
Chair, Northern Alberta Breast Cancer Program
Canadian Leader, Breast Cancer International Research Group
Alberta, Canada
Click here to download the entire interview |
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Track 1 |
Introduction by Dr Love |
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Track 2 |
BCIRG 001: Adjuvant TAC versus FAC for patients with node-positive disease |
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Track 3 |
Effect of nodal status on benefit of TAC |
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Track 4 |
BCIRG 006: Adjuvant AC followed by docetaxel with or without trastuzumab compared to
docetaxel/carboplatin/trastuzumab |
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Track 5 |
Cardiac toxicities observed in BCIRG 006 |
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Track 6 |
Incorporating antiangiogenic agents into the adjuvant setting |
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Track 7 |
Evaluating biological signals in preoperative trials of chemotherapy and antiangiogenic agents |
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Track 8 |
BCIRG 005: TAC versus AC followed by docetaxel as adjuvant therapy |
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Track 9 |
Nonprotocol adjuvant chemotherapy in patients with node-positive disease |
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Track 10 |
AC followed by docetaxel versus dose-dense ACT and TAC |
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Track 11 |
Clinical applicability of MD Anderson neoadjuvant trastuzumab data |
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Track 12 |
Toxicity considerations in the selection of adjuvant hormonal therapy |
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Track 13 |
Nonprotocol selection of adjuvant hormonal therapy for postmenopausal women |
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Track 14 |
Switching from tamoxifen to an aromatase inhibitor after two to three years |
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Track 15 |
Therapeutic decision-making in patients who have completed five years of adjuvant tamoxifen |
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Track 16 |
Up-front use of adjuvant anastrozole |
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Track 17 |
Aromatase inhibitors after two to three years or five years on tamoxifen |
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Track 18 |
Benefits of enrolling patients in clinical trials |
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Track 19 |
Introduction to enclosed slide presentation by Dr Love |
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